Category: Depression
-
The anti-inflammatory effects of Ketamine in treating depression
The mechanism of action that Ketamine affects the brain is certainly extremely complex. Research has shown that Ketamine mediates anti-depression effects via several pathways. One of the most important mechanisms is anti-inflammatory effects. Ketamine can effectively decrease elevated levels of inflammatory markers in both animal models of depression and patients with depression.
-
Gut-brain axis regulates depression
Do you know our body constantly sends signals to our brain that affect our moods? One of the most intriguing findings that scientists discovered was that micro-bacterial flora in the guts can affect communication between our intestines and brain leading to mood disorders via the gut-brain axis.
-
Depression can be treated with Ketamine
Ketamine is an NMDA antagonist, meaning it blocks the NMDA receptor, which is involved in neuroplasticity. Originally licensed by the FDA for use as an anesthetic, ketamine exists in two forms: R-ketamine and S-ketamine. R-ketamine and S-ketamine are enantiomers–two different molecules that are mirror images of each other. S-ketamine, also known as esketamine, comprises the…
-
Inflammation may play a causal role in depression
What is inflammation? You probably never thought inflammation will have anything to do with mental illnesses. Surprisingly, recent search has revealed a causal relationship between inflammation and depression.
-
Depression as a disease
Depression, also known as major depressive disorder (MDD), affects 322 million people worldwide. Approximately 40% of depression is heritable, which leaves room for many influencing factors, such as sex, environment, age, drug use, and socioeconomic status.
Inside the Mind 